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It is possible that some of your directories are not writable by the webserver, log directories may not exist, the unix socket for mod_wsgi not accessible...
In the same directory where you have settings.py
directory log
and askbot/upfiles
must be writable by the apache process.
Also it could be some other error, perhaps you could take a look at apache's default error log as well and maybe system messages: /var/log/messages
Usually there is an error logged somewhere, unless your logging level is set to ignore writing messages.